This course describes the use of different imaging modalities to study brain function and connectivity. The first part of the course deals with brain function. It includes an introduction to energy metabolism in the brain, cerebral blood flow, and brain activation. It continues with an introduction to magnetic resonance imaging (MRI), perfusion-based fMRI, BOLD fMRI, fMRI paradigm design and statistical analysis, introduction to positron emission tomography (PET) and studying brain function with PET, introduction to magneto encephalography and studying brain function with (MEG). The second part of the course deals with brain connectivity. It includes an introduction to diffusion tensor MRI, explanation to the relationship between the diffusion properties of tissue and its structural characteristics, white matter fiber tractography.
[(BME 315 with min. grade of D and PHYS 221 with min. grade of D)]