This course describes the use of different imaging modalities to study brain function and connectivity. The first part of the course deals with brain function. It includes an introduction to energy metabolism in the brain, cerebral blood flow, and brain activation. It continues with an introduction to magnetic resonance imaging (MRI), perfusion-based fMRI, Bold fMRI, fMRI paradigm design and statistical analysis, introduction to positron emission tomography, (PET) and studying brain function with PET, introduction to magneto encephalography (MEG) and studying brain function with MEG. The second part of the deals with brain connectivity. It includes an introduction to diffusion tensor MRI, explanation of the relationship between the diffusion properties of tissue its structural characteristics, and white matter fiber tractography techniques. Instructor permission required.